1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is often an impurity associated with bortezomib, a proteasome inhibitor Utilized in the treatment of numerous myeloma. Its synthesis or analyze is crucial for ensuring the purity and safety from the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor during the synthesis of abiraterone acetate, a drug Employed in the treatment of prostate most cancers by inhibiting androgen production.
Imatinib Intermediate (CAS NO. 152460-10-one): A vital compound within the synthesis of imatinib, a drug that targets unique types of most cancers, including Serious myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Employed in the synthesis of docetaxel, a chemotherapy medication that treats a variety of cancers for instance breast, lung, and prostate cancer.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): These are intermediates in the synthesis of gemcitabine, an anti-cancer drug. Their review is essential for optimizing the generation procedure and making sure large purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-5): Lapatinib is utilised to deal with breast most cancers, and these intermediates are involved with its output.
Fulvestrant Intermediates: Fulvestrant is surely an estrogen receptor antagonist Employed in the remedy of breast cancer. Numerous intermediates assist in the synthesis of the drug.
Paclitaxel Side Chain Acid (CAS NO. 949023-16-nine): This intermediate is Employed in the synthesis of paclitaxel, a chemotherapy drug efficient in managing cancers which include ovarian, breast, and lung cancer.
three. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug used in the treatment method of colorectal most cancers and little mobile lung cancer.
3-Amino-one-hydroxyadamantane (CAS 702-82-nine): This compound is involved in the synthesis of adamantane derivatives, which have a variety of apps, including antiviral Qualities.
Vildagliptin Intermediates: Utilized in the manufacture of vildagliptin, an oral drug for 5R)-3-Benzoyl-2-(4-methoxyphenyl)-4-phenyl-5-oxazolidinecarboxylic acid sort two diabetic issues that inhibits the enzyme DPP-four to control blood sugar levels.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-one): This compound is linked to the synthesis of assorted gluconic acid derivatives, which can be Utilized in foods, pharmaceutical, and industrial programs.
Canagliflozin Intermediate 2: A precursor inside the synthesis of canagliflozin, a medication utilized to manage sort 2 diabetes by inhibiting sodium-glucose co-transporter 6-Piperidinedione 2 (SGLT2).